And when he broke the seventh seal, there was silence in heaven for about half an hour. And I saw the seven angels who stand before God; and seven trumpets were given to them. And another angel came and stood at the altar, holding a golden censer; and much incense was given to him, that he might add it to the prayers of all the saints upon the golden altar which was before the throne. And the smoke of the incense, with the prayers of the saints, went up before God out of the angel's hand. And the angel took the censer; and he filled it with the fire of the altar and threw it to the earth; and there followed peals of thunder and sounds and flashes of lightning and an earthquake.

Prayer and the Consummation of History 

The utterly astonishing thing about this text is that it portrays the prayers of the saints as the instrument God uses to usher in the end of the world with great divine judgments. It pictures the prayers of the saints accumulating on the altar before the throne of God until the appointed time when they are taken up like fire from the altar and thrown upon the earth to bring about the consummation of God's kingdom.
In other words, what we have in this text is an explanation of what has happened to the millions upon millions of prayers over the last 2,000 years as the saints have cried out again and again, "Thy kingdom come . . . Thy kingdom come." Not one of these prayers, prayed in faith, has been ignored. Not one is lost or forgotten. Not one has been ineffectual or pointless. They have all been gathering on the altar before the throne of God.
And the flame has been growing brighter and brighter and more and more pleasing in the presence of God. And the time will come when God will command his holy angel to take his mighty censer and fill it with fire from the altar where the prayers burn before the Lord, and pour it out on the world to bring all God's great and holy purposes to completion. Which means that the consummation of history will be owing to the supplication of the saints who cry to God day and night. Not one God-exalting prayer has ever been in vain.
This is an astonishing tribute to the enormous historical importance of prayer. Now let me stand back with you and see that this is so. Let's go back and get the flow of John's thought in front of us before we look in more detail at the text.
...

What Others Have Said About This Passage 

Listen to what others have said about this passage:
The fire comes from the very altar on which the prayers of the saints have been offered. This surely means that the prayers of God's people play a necessary part in ushering in the judgments of God. "What are the real master-powers behind the world and what are the deeper secrets of our destiny? Here is the astonishing answer: the prayers of the saints and the fire of God. That means that more potent, more powerful than all the dark and mighty powers let loose in the world, more powerful than anything else, is the power of prayer set ablaze by the fire of God and cast upon the earth." (Thomas Torrance, quoted in Morris, Revelation, p. 121)
The events that follow this episode of incense-offering, as one trumpet after another sounds, are the answer to these prayers of the suffering, expectant Church. (Isbon Beckwith, The Apocalypse of John, p. 552)
This verse [5] dramatically pictures the fact that it is in answer to the prayers of the saints that God's judgments will fall upon the earth. (George Ladd, A Commentary on the Revelation of John, p. 125f.)
What God wants us to believe about our God-exalting prayers is that none of them is lost. None is wasted or pointless. They are stored up on the altar of God until the proper time when God pours them out on the earth to accomplish his great purposes of judgment and redemption.
...